产品详情
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Product Name
CD8 alpha Rabbit mAb
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Gene ID
925
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SwissProt ID
P01732
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Gene Name
CD8A
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Alternative Names
MAL, CD8a
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Background
CD8a is an integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, CD8a serves primarily as a coreceptor for MHC class I molecule: peptide complex and its function are involved with lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs). In NK-cells, the presence of CD8a homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8a homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
IHC-P,FC
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Dilution Ratio
IHC-P：1/50-1/100，FC：1/50
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Molecular Weight
–
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Clonality
Monoclonal Antibody
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Clonality No.
R07-6R-8
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Isotype
IgG
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Immunogen
Peptide
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Purification
Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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