产品详情
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Product Name
LOX1 Rabbit mAb
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Gene ID
4973
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SwissProt ID
P78380
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Gene Name
OLR1
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Alternative Names
OLR1, CLEC8A
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Background
This protein is a low density lipoprotein receptor that belongs to the C-type lectin superfamily. It is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. Diseases associated with OLR1 include Myocardial Infarction and Chlamydia Pneumonia. Among its related pathways are Innate Immune System and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and low-density lipoprotein particle receptor activity.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,ICC/IF,FC
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Dilution Ratio
WB:1/500-1/1000,ICC/IF:1/50,FC:1/50-1/100
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Molecular Weight
Calculated MW: 31 kDa; Observed MW:55 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R09-1S-8
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Isotype
IgG
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Immunogen
Peptide
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Purification
Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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