产品详情
-
Product Name
4-1BB Rabbit mAb
-
Gene ID
3604
-
SwissProt ID
Q07011
-
Gene Name
TNFRSF9
-
Alternative Names
TNFRSF9; 4-1BB; CD137; CDw137; ILA
-
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
-
Research Field
Immunology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
FC,ELISA
-
Dilution Ratio
FC: 1/50-1/100 ELISA: 1/10000
-
Molecular Weight
-
-
Clonality
Monoclonal Antibody
-
Clonality No.
R05-7H-2
-
Isotype
IgG
-
Immunogen
Recombinant human 4-1BB protein
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Lyophilized
-
Buffer System
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
Storage
Store at -20°C to -80°C for 12 months in lyophilized form.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用,请参照上方的缩写含义,仔细对照后选择合适的产品。