货号： R10021
别名： EndoCAM, GPIIA', PECA1, PECAM1, PECAM-1
应用： WB,IHC-P,ICC/IF,FC
反应种属： Human
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    CD31 Rabbit mAb
  • Gene ID
    5175
  • SwissProt ID
    P16284
  • Gene Name
    PECAM1
  • Alternative Names
    EndoCAM, GPIIA', PECA1, PECAM1, PECAM-1
  • Background
    Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils. Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal. Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells.
  • Research Field
    Tumor biology
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human
  • Application
    WB,IHC-P,ICC/IF,FC
  • Dilution Ratio
    WB：1/500-1/1000，IHC-P：1/50-1/100，ICC/IF：1/50，FC：1/50-1/100
  • Molecular Weight
    Calculated MW: 83 kDa; Observed MW:125 kDa
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    R07-4R-3
  • Isotype
    IgG
  • Immunogen
    Peptide
  • Purification
    Protein A
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Liquid in PBS, Glycerol and BSA
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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