产品详情
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Product Name
HDAC1 Rabbit mAb
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Gene ID
3065
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SwissProt ID
Q13547
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Gene Name
HDAC1
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Alternative Names
HD1, RPD3L1
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Background
Histone deacetylase 1 (HDAC1) is an enzyme that is encoded by the HDAC1 gene in human. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2 MTA2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB：1/500-1/1000 IHC-P：1/50-1/100
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Molecular Weight
Calculated MW: 55 kDa; Observed MW:65 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-6F-9
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Isotype
IgG/Kappa
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Immunogen
Peptide
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Purification
Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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