产品详情
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Product Name
Human HMGB1 Protein
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Gene ID
3146
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SwissProt ID
P09429
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Gene Name
HMGB1
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Alternative Names
HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
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Background
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Protein
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Host
E-coli
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Reactivity
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Application
Functional Assay
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Dilution Ratio
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Molecular Weight
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Clonality
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Clonality No.
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Isotype
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Immunogen
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Immunogen Alternative Names
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
His
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Form
lyophilized
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Buffer System
0.01M PBS, pH 7.2
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Storage
Aliquot and store at -80°C for long term. Avoid freeze/thaw cycles.
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Target
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应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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