货号： PD201086
别名： FLT3; CD135; FLK2; STK1; Receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; Fetal liver kinase-2; FLK-2; Fms-like tyrosine kinase 3; FLT-3; Stem cell tyrosine kinase 1; STK-1; CD antigen CD135
应用： Functional Assay
反应种属： -
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Human FLT-3 Ligand Protein
  • Gene ID
    2322
  • SwissProt ID
    P36888
  • Gene Name
    FLT3
  • Alternative Names
    FLT3; CD135; FLK2; STK1; Receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; Fetal liver kinase-2; FLK-2; Fms-like tyrosine kinase 3; FLT-3; Stem cell tyrosine kinase 1; STK-1; CD antigen CD135
  • Background
    This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
  • Research Field
    Immunology
  • Product Categories
    Protein
  • Host
    E-coli
  • Reactivity
    -
  • Application
    Functional Assay
  • Dilution Ratio
    -
  • Molecular Weight
    -
  • Clonality
    -
  • Clonality No.
    -
  • Isotype
    -
  • Immunogen
    -
  • Immunogen Alternative Names
    -
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    His
  • Form
    lyophilized
  • Buffer System
    0.01M PBS, pH 7.2
  • Storage
    Aliquot and store at -80°C for long term. Avoid freeze/thaw cycles.
  • Target
    -
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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