产品详情
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Product Name
Human IL-7 Protein
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Gene ID
3574
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SwissProt ID
P13232
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Gene Name
IL7
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Alternative Names
IL7;IL-7; interleukin 7
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Background
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
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Research Field
Immunology
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Product Categories
Protein
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Host
E-coli
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Reactivity
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Application
Functional Assay
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Dilution Ratio
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Molecular Weight
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Clonality
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Clonality No.
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Isotype
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Immunogen
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Immunogen Alternative Names
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
His
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Form
lyophilized
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Buffer System
0.01M PBS, pH 7.2
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Storage
Aliquot and store at -80°C for long term. Avoid freeze/thaw cycles.
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Target
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应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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