产品详情
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Product Name
Mouse IL-10 Protein
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Gene ID
16153
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SwissProt ID
P18893
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Gene Name
IL-10
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Alternative Names
Il10;Il-10;Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF
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Background
L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4.
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Research Field
Immunology
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Product Categories
Protein
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Host
E-coli
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Reactivity
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Application
Functional Assay
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Dilution Ratio
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Molecular Weight
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Clonality
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Clonality No.
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Isotype
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Immunogen
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Immunogen Alternative Names
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
His
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Form
lyophilized
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Buffer System
0.01M PBS, pH 7.2
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Storage
Aliquot and store at -80°C for long term. Avoid freeze/thaw cycles.
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Target
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应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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