产品详情
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Product Name
MCP-1 Rabbit mAb, unconjugated, detector
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Gene ID
6347
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SwissProt ID
P13500
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Gene Name
CCL2
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Alternative Names
HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
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Background
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
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Research Field
Immunology
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Product Categories
Antibody Pair
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Host
Rabbit
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Reactivity
Human
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Application
ELISA
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Dilution Ratio
Determined by end user
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
R08-2Y4
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Isotype
IgG
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Immunogen
Recombinant protein
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
0.01M PBS, pH 7.2
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Storage
Store at 4°C for at least 12 months. Avoid freeze/thaw cycles
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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