产品详情
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Product Name
alpha 1 Fetoprotein Mouse mAb, capture
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Gene ID
174
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SwissProt ID
P02771
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Gene Name
AFP
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Alternative Names
FETA; HPAFP
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Background
Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .
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Research Field
Cancer
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Product Categories
Antibody Pair
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Host
Mouse
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Reactivity
Human
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Application
ELISA
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Dilution Ratio
ELISA: 1/1000
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
3C11
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Isotype
IgG1
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Immunogen
A synthesized peptide derived from AFP
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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