产品详情
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Product Name
IL-6 Rabbit mAb,capture
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Gene ID
3569
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SwissProt ID
P05231
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Gene Name
IL6
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Background
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
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Research Field
Immunology
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Product Categories
Antibody Pair
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Host
Rabbit
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Reactivity
Human
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Application
ELISA
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Dilution Ratio
Determined by end user
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
R02-8S-1
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Isotype
IgG
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Immunogen
Recombinant protein
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
0.01M PBS, pH 7.2
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Storage
Store at 4°C for at least 12 months. Avoid freeze/thaw cycles
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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