产品详情
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Product Name
Endostatin Mouse mAb, unconjugated, detector
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Gene ID
80781
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SwissProt ID
P39060
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Gene Name
COL18A1
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Alternative Names
KS; Endostatin; KNO; KNO1
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Background
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Research Field
Cardiovascular
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Product Categories
Antibody Pair
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Host
Mouse
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Reactivity
Human
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Application
ELISA
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Dilution Ratio
ELISA: 1/1000
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Molecular Weight
-
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Clonality
Monoclonal Antibody
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Clonality No.
5E3
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Isotype
IgG2a
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Immunogen
A synthesized peptide derived from endostatin
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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