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货号： 250011

别名： H3 histone; HIST1H3A; Histone cluster 1; H3a

应用： WB,IHC-F,IHC-P,ICC/IF,IP

反应种属： Human,Mouse,Rat,Yeast

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：现货说明书PDF

产品详情

Product Name

Histone H3 (6G2) Mouse mAb
Gene ID

8350
SwissProt ID

P68431
Gene Name

H3C1
Alternative Names

H3 histone; HIST1H3A; Histone cluster 1; H3a
Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.MiscellaneousThis histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2).
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Loading Control antibody
Host

Mouse
Reactivity

Human,Mouse,Rat,Yeast
Application

WB,IHC-F,IHC-P,ICC/IF,IP
Dilution Ratio

WB: 1/5000-1/10000 IHC: 1/50-1/200 IF: 1/100-1/200 IP: 1/20
Molecular Weight

Calculated MW: 15 kDa; Observed MW: 15 kDa
Clonality

Monoclonal Antibody
Clonality No.

6G2-5A6-6C1
Isotype

IgG1
Immunogen

Recombinant Protein of Histone H3
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

标题： Novel quantitative immunohistochemistry method using histone H3, family 3B as the internal reference standard for measuring human epidermal growth factor receptor 2 expression in breast cancer

样本种属： Human

杂志： CANCER

应用： IHC

IF： 6.2

文献链接

标题： Geniposide restricts angiogenesis in experimentary arthritis via inhibiting Dnmt1-mediated PTEN hypermethylation

样本种属： Human,Rat

杂志： INTERNATIONAL IMMUNOPHARMACOLOGY

应用： WB,IHC

IF： 5.714

文献链接