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Product Name
hCXCR1 full length protein-synthetic nanodisc
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Gene ID
3577
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SwissProt ID
P25024
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Gene Name
CXCR1,CMKAR1, IL8RA
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Alternative Names
C-C; C-C-CKR-1; CD128; CD181; CDw128a; CKR-1; CMKAR1; IL8R1; IL8RA; IL8RBA
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Background
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]
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Research Field
Signal Transduction
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Product Categories
Full Length Transmembrane Proteins
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Host
HEK293 Cells
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Reactivity
Human
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Application
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Dilution Ratio
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Molecular Weight
The human full length CXCR1 protein has a MW of 39.8 kDa
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Form
Freeze-dried powder
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Buffer System
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
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Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Target
CXCR1