-
Product Name
hACM1 full length protein-synthetic nanodisc
-
Gene ID
1128
-
SwissProt ID
P11229
-
Gene Name
CHRM1
-
Background
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
-
Research Field
Cell Biology & Developmental Biology
-
Product Categories
Full Length Transmembrane Proteins
-
Host
HEK293 Cells
-
Reactivity
Human
-
Application
-
Dilution Ratio
-
Molecular Weight
The human full length ACM1 protein has a MW of 51.4kDa
-
Form
Freeze-dried powder
-
Buffer System
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
-
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
Target
ACM1