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Product Name
h5HT1F full length protein-synthetic nanodisc
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Gene ID
3355
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SwissProt ID
P30939
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Gene Name
HTR1F,HTR1EL
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Background
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.[UniProtKB/Swiss-Prot Function]
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Research Field
Signal Transduction
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Product Categories
Full Length Transmembrane Proteins
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Host
HEK293 Cells
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Reactivity
Human
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Application
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Dilution Ratio
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Molecular Weight
The human full length 5HT1F protein has a MW of 41.7kDa
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Form
Freeze-dried powder
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Buffer System
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
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Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Target
5HT1F