-
Product Name
hCLPTM1 full length protein-synthetic nanodisc
-
Gene ID
1209
-
SwissProt ID
O96005
-
Gene Name
CLPTM1
-
Background
Involved in GABAergic but not glutamatergic transmission. Binds and traps GABAA receptors in the endoplasmic reticulum (ER). Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors. Altered GABAergic signaling is one among many causes of cleft palate. Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one.
-
Research Field
Cell Biology
-
Product Categories
Full Length Transmembrane Proteins
-
Host
HEK293 Cells
-
Reactivity
Human
-
Application
-
Dilution Ratio
-
Molecular Weight
The human full length CLPTM1 protein has a MW of 76.1 kDa
-
Form
Freeze-dried powder
-
Buffer System
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
-
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
Target
CLPTM1