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Product Name
[KO] Rab5 Rabbit mAb
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Gene ID
5868
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SwissProt ID
P20339
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Gene Name
RAB5A
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Alternative Names
RAB5A; RAB5; RAS associated protein RAB5A; Ras related protein Rab 5A
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Background
Rab5 is a member of the Ras superfamily of small Rab GTPases. Rab5 is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis (1). The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis.
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Research Field
Neuroscience
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Product Categories
KO/KD validated
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 24 kDa; Observed MW: 24 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R06-4J3
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Isotype
IgG
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Immunogen
A synthetic peptide of human Rab5
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.