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Product Name
[KD] GSK3 alpha/beta Rabbit mAb
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Gene ID
2931
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SwissProt ID
P49840
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Gene Name
GSK3A
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Alternative Names
Serine/threonine-protein kinase GSK3A
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Background
GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
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Research Field
Neuroscience
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Product Categories
KO/KD validated
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Host
Rabbit
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Reactivity
Human,Rat,Hamster
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 51 kDa; Observed MW: 51,47 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-8G7
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Isotype
IgG
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Immunogen
A synthetic peptide of human GSK3 alpha
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.