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Product Name
[KO] Caldesmon Rabbit mAb
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Gene ID
800
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SwissProt ID
Q05682
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Gene Name
CALD1
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Alternative Names
CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22
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Background
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin.
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Research Field
Cell Biology
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Product Categories
KO/KD validated
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
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Molecular Weight
Calculated MW: 93 kDa; Observed MW: 70-80 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R05-3D2
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Isotype
IgG
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Immunogen
A synthetic peptide of human Caldesmon
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.