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Product Name
[KO] PI3 Kinase p110 beta Rabbit mAb
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Gene ID
5291
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SwissProt ID
P42338
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Gene Name
PIK3CB
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Alternative Names
PIK3CB; DKFZp779K1237; MGC133043; PI3K; PI3KCB; PI3Kbeta; PIK3C1; p110-BETA
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Background
Phosphoinositide 3-kinase (PI3K) catalyzes the production of phosphatidylinositol-3,4,5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP) and phosphatidylinositol-4,5-bisphosphate (PIP2). Growth factors and hormones trigger this phosphorylation event, which in turn coordinates cell growth, cell cycle entry, cell migration, and cell survival.
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Research Field
Cell Biology
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Product Categories
KO/KD validated
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Host
Rabbit
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Reactivity
Human
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Application
WB,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
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Molecular Weight
Calculated MW: 123 kDa; Observed MW: 110 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R03-5K7
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Isotype
IgG
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Immunogen
A synthetic peptide of human PI3 Kinase p110 beta
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.