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Product Name
[KD] Cleaved-Caspase 9 Rabbit mAb
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Gene ID
842
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SwissProt ID
P55211
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Gene Name
CASP9
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Alternative Names
CASP9; MCH6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6
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Background
Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit.
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Research Field
Cell Biology
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Product Categories
KO/KD validated
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,IHC-P,ICC/IF,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50
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Molecular Weight
Calculated MW: 46 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R05-4I8
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Caspase-9
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Cleaved
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.