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Product Name
[KO] PAR4 Rabbit mAb
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Gene ID
5074
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SwissProt ID
Q96IZ0
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Gene Name
PAWR
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Alternative Names
PAWR; PAR4; PRKC apoptosis WT1 regulator protein; Prostate apoptosis response 4 protein; Par-4
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Background
Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity.
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Research Field
Cell Biology
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Product Categories
KO/KD validated
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
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Molecular Weight
Calculated MW: 37 kDa; Observed MW: 41 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-8C0
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Isotype
IgG
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Immunogen
A synthetic peptide of human PAR4
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.