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Product Name
[KO] Hsp40 Mouse mAb
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Gene ID
3337
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SwissProt ID
P25685
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Gene Name
DNAJB1
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Alternative Names
DNAJB1; DNAJ1; HDJ1; HSPF1; DnaJ homolog subfamily B member 1; DnaJ protein homolog 1; Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40; Human DnaJ protein 1; hDj-1
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Background
Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response (PubMed:9499401). Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro).
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Research Field
Signal Transduction
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Product Categories
KO/KD validated
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Host
Mouse
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P,FC
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 38 kDa; Observed MW: 38 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
1000000000
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Isotype
IgG2a
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Immunogen
Full length human recombinant protein of human DNAJB1 produced in 293T cell.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.