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Product Name
[KO] NMI Mouse mAb
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Gene ID
9111
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SwissProt ID
Q13287
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Gene Name
NMI
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Alternative Names
N-myc (and STAT) interactor; N-myc-interactor; N-myc and STAT interactor; N-myc interactor
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Background
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]
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Research Field
Tags & Cell Markers
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Product Categories
KO/KD validated
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Host
Mouse
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Reactivity
Human
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 35 kDa; Observed MW: 37 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
2C1
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Isotype
IgG2b
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Immunogen
Purified recombinant human NMI protein fragments expressed in E.coli.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.