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Product Name
[KO] USP10 Mouse mAb
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Gene ID
9100
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SwissProt ID
Q14694
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Gene Name
USP10
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Alternative Names
Deubiquitinating enzyme 10; UBPO; USP10
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Background
Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.
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Research Field
Cell Biology
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Product Categories
KO/KD validated
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Host
Mouse
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Reactivity
Human
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Application
WB,IHC-P,FC
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 87 kDa; Observed MW: 120 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
1A10
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Isotype
IgG2a
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Immunogen
Full length human recombinant protein of human USP10 produced in 293T cell.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.