-
Product Name
[KO] hnRNP F Mouse mAb
-
Gene ID
3185
-
SwissProt ID
P52597
-
Gene Name
HNRNPF
-
Alternative Names
HNRPF; mcs94-1; OK/SW-cl.23
-
Background
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
KO/KD validated
-
Host
Mouse
-
Reactivity
Human,Mouse,Rat
-
Application
WB,IHC-P,ICC/IF,FC
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200 FC: 1/50-1/100
-
Molecular Weight
Calculated MW: 46 kDa; Observed MW: 46 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
5F5
-
Isotype
IgG2a
-
Immunogen
Full length human recombinant protein of human HNRNPF produced in 293T cell.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.