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Product Name
[KO] Fascin Mouse mAb
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Gene ID
6624
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SwissProt ID
Q16658
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Gene Name
FSCN1
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Alternative Names
55 kDa actin bundling protein; Actin bundling protein; FAN1; Fascin 1; Fascin; Singed (Drosophila) like (sea urchin fascin homolog like); Fascin homolog 1; Fascin
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Background
Promotes cross-linkage of parallel actin filaments during the formation of cell protrusions (lamellipodia and filopodia), and therefore plays an important role in regulating cell migration. It has been reported that fascin may also regulate filopodia formation by a mechanism independent of its actin-bundling functions, though less is known about this mechanism of action.
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Research Field
Cell Biology
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Product Categories
KO/KD validated
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Host
Mouse
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 55 kDa; Observed MW: 55 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
3D2
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Isotype
IgG2a
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Immunogen
Full length human recombinant protein of human FSCN1 produced in 293T cell.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.