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Product Name
[KO] delta Catenin Mouse mAb
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Gene ID
1500
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SwissProt ID
O60716
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Gene Name
CTNND1
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Alternative Names
CAS; p120; BCDS2; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)
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Background
Catenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion.
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Research Field
Cell Biology
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Product Categories
KO/KD validated
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Host
Mouse
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 108 kDa; Observed MW: 108 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
2G7
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Isotype
IgG1
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Immunogen
Full length human recombinant protein of human CTNND1 produced in 293T cell.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.