货号: 240026
别名: CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
应用: WB,IHC-P,ICC/IF,FC
反应种属: Human,Mouse,Rat
目录价格:
RMB(含税报价)
数量: - + (库存件)
查看代理商 预计货期:3-4个工作日 说明书PDF
产品详情
  • Product Name
    [KO] Chk2 Mouse mAb
  • Gene ID
    11200
  • SwissProt ID
    O96017
  • Gene Name
    CHEK2
  • Alternative Names
    CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
  • Background
    These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
  • Research Field
    Epigenetics and Nuclear Signaling
  • Product Categories
    KO/KD validated
  • Host
    Mouse
  • Reactivity
    Human,Mouse,Rat
  • Application
    WB,IHC-P,ICC/IF,FC
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200 FC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 61 kDa; Observed MW: 61 kDa
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    5C4
  • Isotype
    IgG1
  • Immunogen
    Full length human recombinant protein of human CHEK2 produced in 293T cell.
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用,请参照上方的缩写含义,仔细对照后选择合适的产品。
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