-
Product Name
[KO] USB1 Mouse mAb
-
Gene ID
79650
-
SwissProt ID
Q9BQ65
-
Gene Name
USB1
-
Alternative Names
C16orf57; hUsb1; HVSL1; Mpn1; PN
-
Background
This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]
-
Research Field
Cell Biology
-
Product Categories
KO/KD validated
-
Host
Mouse
-
Reactivity
Human
-
Application
WB
-
Dilution Ratio
WB: 1/500-1/1000
-
Molecular Weight
Calculated MW: 30 kDa; Observed MW: 34 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
1B1
-
Isotype
IgG2b
-
Immunogen
Full length human recombinant protein of human USB1 produced in E.coli.
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.