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Product Name
[KO] SIRT5 Mouse mAb
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Gene ID
23408
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SwissProt ID
Q9NXA8
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Gene Name
SIRT5
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Alternative Names
SIR2-like protein 5; SIR2L5; Sirt5; Sirtuin 5; Sirtuin type 5
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Background
The Silent Information Regulator (SIR2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as Class III histone deacetylases. SirT5, a mammalian homolog of Sir2, is localized to the mitochondria and has been implicated in the regulation of cell metabolism.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
KO/KD validated
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Host
Mouse
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 34 kDa; Observed MW: 34 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
2F1
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Isotype
IgG1
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Immunogen
Full length human recombinant protein of human SIRT5 produced in 293T cell.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.