产品详情
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Product Name
[KO] IRF3 Mouse mAb
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Gene ID
3661
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SwissProt ID
Q14653
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Gene Name
IRF3
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Alternative Names
IRF3; Interferon regulatory factor 3; IRF-3
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Background
IRFs comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection. IRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response.
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Research Field
Signal Transduction
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Product Categories
KO/KD validated
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Host
Mouse
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Reactivity
Human,Monkey
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 47 kDa; Observed MW: 56 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
5D2
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Isotype
IgG2b
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Immunogen
Full length human recombinant protein of human IRF3 produced in 293T cell.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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